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英文名：ICG NHS ester

ICG-OSu 

中文名：ICG-琥珀酰亚胺酯
CAS: 1622335-40-3

分子式: C49H53N3O7S

分子量: 828.03

外 观：深绿色粉末

溶解性：溶于DMSO或DMF

纯 度：95%

保 存：-20℃避光

激发发射波长:785/821nm

描 述：ICG is a NIR fluorescent substance which obtain license for clinical uses from US FDA(/article/11/) (Food and Drug administration), along with Methylene Blue. It is used in Ophthalmologic angiography, liver function tests, solid tumor detection in surgical operation and angiography.

Because ICG effectively absorbs near infrared wavelength that is about 800nm and its absorption ratio for wavelength of visible light range is low, noises caused by Autofluorescence is low.

ICG NHS ester is a product that has the most representative NHS ester reactive group for labeling amine. Because it rapidly and high-specifically reacts to Primary amine (-NH2), it can label Protein containing amine (-NH2), Antibody and Amine-modified Oligonucleotide in a short time period.

结构式：

ICG NHS ester的NHS可以和蛋白、多肽或抗体上面的NH2发生反应链接到一起。

ICG-maleimide的马来酰亚胺可以和蛋白、多肽、小分子或抗体上的SH巯基反应连接。

ICG-Amine的NH2可以和蛋白、多肽小分子上面的NHS反应连接起来。

ICG和PEG链接可在体内长循环。

ICG衍生物产品：

ICG的活性基团荧光染料：

ICG NHS ester      

ICG-Vinylsulfone

ICG-Isothiocyanate

ICG-carboxlaic acid

ICG-maleimide

ICG-Amine

Sulfo ICG-NHSester

ICG和PEG修饰的产品：

ICG-PEG-NH2

ICG-PEG-MAL

ICG-PEG-NHS

ICG-PEG-COOH

ICG-PEG-Folate

ICG-PEG-N3

ICG-PEG-SH

ICG-PEG-DSPE